Bioactive Small Molecules
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Filtered Search Results
Medchemexpress LLC 10 mM * 1 mL in DMSO, MK2206 | 1032350-13-2
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10 mM * 1 mL in DMSO, MK2206
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Sigma Aldrich Fine Chemicals Biosciences MDL 105,519 >=98% (HPLC), solid | 161230-88-2 | MFCD00935267 | 5MG
MDL 105,519 >=98% (HPLC), solid | Purity: >=98% (HPLC) | Mol Wt: 376.19 | 161230-88-2 | MFCD00935267 | 5MG
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Selleck Chemical LLC DIABZI STING AGONIST 5MG
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diABZI STING agonist (Compound 3) 5mg *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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GREENHOUSE MEGASTORE 1020 TRAYS,HD,NO DRAIN,100/CS
This heavy duty thermoformed tray is heavier than standard 1020 trays. Design allows community watering of pots, consistent bottom & side positioned drainage holes (or no holes) and easy, two-finger denesting. Both trays come with no center bar or side ribs. Select flats with or without holes.10.94" W x 21.44" L x 2.44" DThermoformed trays designed for consistent performance in automated filling and handling equipment.Don't settle for cheap and flimsy trays. Our 1020 trays are heavy weight and reusable.Used with our inserts to create compact, efficient growing systems for Bedding Plants5 oz eachStarting Thickness: 0.040" gauge (Heavy Duty)Made in the USA
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Abcam 4-Aminopyridine (4-AP), K+ channel blocker, 100MG
MW 94.11 Da, Purity >99%. Potassium channel blocker. Blocks Kv channels. Convulsant, and useful tool to model epileptiform activity *in vitro*.
The product is subject to the following: Abcam Restricted Use Statement
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Apexbio Technology LLC Triptolide, 5mg. Cas: 38748-32-2 MFCD: MFCD00210565. IL-2/MMP-3/MMP7/MMP19 inhibitor
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Triptolide inhibits cytokine-induced gene expression via inhibition of NF-kappaB transcriptional activity. 38748-32-2. MFCD00210565
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Apexbio Technology LLC Dofetilide is a potassium channel blocker. 115256-11-6. MFCD00869707
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Dofetilide is a potassium channel blocker. 115256-11-6. MFCD00869707
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Cell Signaling Technology Etoposide 5.9 mg
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Etoposide 5.9 mg
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STEMCELL Technologies IWP-2, Size: 10 mg
IWP-2 inhibits the WNT pathway (IC₅₀ = 27 nM) at the level of the pathway activator Porcupine. Porcupine is a membrane-bound acyltransferase that palmitoylates WNT proteins, which leads to WNT secretion and signaling capability. (Chen et al., Willert et al.)DIFFERENTIATION· Suppresses self-renewal of mouse embryonic stem (ES) cells and supports their conversion to epiblast-like stem cells (ten Berge et al.).· Inhibits maintenance and proliferation of mouse Lgr5+ intestinal and cochlear epithelial stem cells, demonstrating the importance of WNT signaling in these processes (Chai et al., Farin et al.).· Promotes cardiomyocyte differentiation from human pluripotent stem cells (Lian et al., Minami et al.).
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TARGETMOL CHEMICALS INC POLYQUATERNIUM-1 5MG
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502694054 POLYQUATERNIUM-1 5MG
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TARGETMOL CHEMICALS INC DEUCRAVACITINIB 5MG
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502694167 DEUCRAVACITINIB 5MG
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Abcam MLN-4924, NEDD8-activating enzyme inhibitor, 1MG
MW 443.5 Da, Purity >98%. Potent NEDD8-activating enzyme (NAE) inhibitor (IC₅₀ = 4.7 nM). Selective relative to the closely related activating enzymes ubiquitin-activating enzyme (UAE) and SUMO-activating enzyme (SAE). Adenosine 5'-monophosphate analog. Disrupts cullin-RING ligase (CRL)-mediated protein turnover leading to apoptosis in human tumour cells by deregulating S-phase DNA synthesis.
The product is subject to the following: Abcam Restricted Use Statement
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Medchemexpress LLC GNE-064 | 1997321-20-6 | 99.7% | 327.38 | 25 MG
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GNE-064 is a selective, orally active, and highly soluble inhibitor of SMARCA4, SMARCA2, and PBRM1 bromodomains 5. It functions as a chemical probe for agent synthesis research.
- Selective inhibitor of SMARCA4, SMARCA2, and PBRM1 bromodomains 5
- Orally active and highly soluble
- Inhibits SMARCA4 with an IC50 of 0.035 μM
- Inhibits SMARCA2 with an EC50 of 0.10 μM
- Suitable as a chemical probe for agent synthesis research
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Medchemexpress LLC Thalidomide (standard) | 50-35-1 | 99.96% | 258.23 | 25 MG
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Thalidomide (Standard) is the analytical standard of Thalidomide, used for research and analytical applications. It inhibits cereblon (CRBN) with a Kd of approximately 250 nM, and has immunomodulatory, anti-inflammatory, and anti-angiogenic cancer properties. It can also function as a molecular glue to potentiate substrates.
- Analytical standard grade
- For research and analytical applications
- Inhibits cereblon (CRBN) with Kd of approximately 250 nM
- Immunomodulatory, anti-inflammatory, and anti-angiogenic cancer properties
- Functions as a molecular glue to potentiate substrates
- Used in qualitative, quantitative, and methodological research experiments (HPLC, GC, MS)
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Medchemexpress LLC (E)-Akt inhibitor-IV | 959841-49-7 | 98.6% | 614.54 | 1 ML
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(E)-Akt inhibitor-IV ((E)-AKTIV) is a PI3K-Akt inhibitor with potent cytotoxic properties. It is intended for research use only and is not sold to patients.
- Acts as a PI3K-Akt inhibitor
- Exhibits potent cytotoxic properties
- Shows an average GI20 of 0.04 μM on four cell lines including MDA-MB468, MDA-MB231, MCF7, and 184B5 cells
- Has little effect on the growth of 184B5 non-cancer cells at average GI20 doses
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